INO
CNR
vai_a_storia   vai_a_organizzazione   vai_a_sedi   vai_a_personale   Area Riservata
    English English Version  
 
 

Improved cell activity on biodegradable photopolymer scaffolds using titanate nanotube coatings

  Articoli su Riviste JCR/ISI  (anno 2014)

Autori:  Beke S., Barenghi R., Farkas B., Romano I., Kőrösi L., Scaglione S., Brandi F

Affiliazione Autori:  Nanophysics, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy; IEIIT, National Research Council (CNR), Via De Marini 6, 16149 Genova, Italy; Department of Biotechnology, Nanophage Therapy Center, Enviroinvest Corporation, Kertváros u. 2, H-7632 Pécs, Hungary; Istituto Nazionale di Ottica, CNR, Via G. Moruzzi 1, 56124-Pisa, Italy

Riassunto:  The development of bioactive materials is in the premise of tissue engineering. For several years, surface functionalization of scaffolds has been one of the most promising approaches to stimulate cellular activity and finally improve implant success. Herein, we describe the development of a bioactive composite scaffold composed of a biodegradable photopolymer scaffold and titanate nanotubes (TNTs). The biodegradable photopolymer scaffolds were fabricated by applying mask-projection excimer laser photocuring at 308 nm.TNTs were synthesized and then spin-coated on the porous scaffolds. Upon culturing fibroblast cells on scaffolds, we found that nanotubes coating affects cell viability and proliferation demonstrating that TNT coatings enhance cell growth on the scaffolds by further improving their surface topography. (C) 2014 Elsevier B.V. All rights reserved.

Rivista/Giornale:  MATERIALS SCIENCE & ENGINEERING. C, MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume n.:  44      Pagine da: 38  a: 43
Ulteriori informazioni:  The authors are thankful for Alice Scarpellini and Paola Gavazzo for assisting in SEM imaging and cell culture experiments, respectively. This work has been supported in part by the European Community (FP7-NMP-2013-EU-China) grant agreement no. 604263 (NEUROSCAFFOLDS).
DOI: 10.1016/j.msec.2014.07.008

*Impact Factor della Rivista: (2014) 3.088   *Citazioni: 14
data tratti da "WEB OF SCIENCE" (marchio registrato di Thomson Reuters) ed aggiornati a:  26/05/2019

Riferimenti visionabili in IsiWeb of Knowledge: (solo per sottoscrittori)
Per visualizzare la scheda dell'articolo su IsiWeb: Clicca qui
Per visualizzare la scheda delle Citazioni dell'articolo su IsiWeb: Clicca qui

INO © Istituto Nazionale di Ottica - Largo Fermi 6, 50125 Firenze | Tel. 05523081 Fax 0552337755 - P.IVA 02118311006     P.E.C.    Info